(19)

(11)

EP 4 142 688 A1

(12)

(43) Date of publication: 08.03.2023 Bulletin 2023/10 (21) Application number: 21727063.6 (22) Date of filing: 03.05.2021

(51) International Patent Classification (IPC):  A61K 9/00(2006.01) A61K 33/04(2006.01) A61K 9/08(2006.01) (52) Cooperative Patent Classification (CPC): A61K 9/0078; A61K 9/08; A61K 33/04; A61P 31/14; A61P 11/00; Y02A 50/30 (86) International application number: PCT/US2021/030429 (87) International publication number: WO 2021/222884 (04.11.2021 Gazette 2021/44)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 01.05.2020 US 202063019258 P 04.12.2020 US 202063121856 P 01.02.2021 US 202163144305 P (71) Applicant: Tygrus LLC Troy, Michigan 48083 (US)	(72) Inventors: CARLSON, Lawrence Troy, Michigan 48083 (US) ATALA, Anthony Troy, Michigan 48083 (US) SCALERA, Patrick Troy, Michigan 48083 (US) YAKSIC, Andrew Troy, Michigan 48083 (US) (74) Representative: Graham Watt & Co LLP  St. Botolph's House 7-9 St. Botolph's Road Sevenoaks TN13 3AJ Sevenoaks TN13 3AJ (GB)