(19)

(11)

EP 4 142 945 A2

(12)

(88) Date of publication A3: 09.12.2021 (43) Date of publication: 08.03.2023 Bulletin 2023/10 (21) Application number: 21723396.4 (22) Date of filing: 28.04.2021

(51) International Patent Classification (IPC):  B01L 7/00(2006.01) C12Q 1/70(2006.01) C12Q 1/68(2006.01) (52) Cooperative Patent Classification (CPC): B01L 7/52; B01L 2300/0663; B01L 2300/1822; B01L 2300/1827; B01L 2300/023; C12Q 1/701 (86) International application number: PCT/IB2021/053530 (87) International publication number: WO 2021/220192 (04.11.2021 Gazette 2021/44)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 30.04.2020 PT 2020116317 (71) Applicant: Stab Vida - Investigação e Serviços em Ciências Biológicas Lda 2825-182 Caparica (PT)	(72) Inventors: DE LEÃO E FLORES, Alcino Orfeu 2820-491 Charneca da Caparica (PT) REIMÃO PINTO DE FRANÇA DORIA, Gonçalo Maria 2725-329 Mem Martins (PT) (74) Representative: Pereira Garcia, João Luís  Simões, Garcia, Corte-Real e Associados Rua Castilho, 167, 2° 1070-050 Lisboa 1070-050 Lisboa (PT)