(19)
(11) EP 4 146 809 A1

(12)

(43) Date of publication:
15.03.2023 Bulletin 2023/11

(21) Application number: 21799490.4

(22) Date of filing: 03.05.2021
(51) International Patent Classification (IPC): 
C12N 15/81(2006.01)
C12N 15/52(2006.01)
C12N 9/88(2006.01)
 C12N 9/10(2006.01)
C12N 9/12(2006.01)
C07C 63/04(2006.01)
(52) Cooperative Patent Classification (CPC):
C12N 15/81; C12N 15/52; C12P 7/22; C12P 7/42; C12Y 404/01026; C12Y 302/01; C12N 9/1029; C12Y 203/01206; C12N 9/88; C12N 9/93; C12R 2001/865; C12N 1/18
(86) International application number:
PCT/US2021/030452
(87) International publication number:
WO 2021/225952 (11.11.2021 Gazette 2021/45)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 08.05.2020 US 202063022038 P
26.08.2020 US 202063070513 P
16.09.2020 US 202063079390 P
09.10.2020 US 202063089736 P
07.12.2020 US 202063122369 P

(71) Applicant: Lygos, Inc.
Berkeley CA 94710 (US)

(72) Inventors:
  • OHLER, Nick
    Berkeley, California 94710 (US)
  • CONLEY, Andrew
    Berkeley, California 94710 (US)
  • FARINA, Anthony
    Berkeley, California 94710 (US)
  • OUELLET, Mario
    Berkeley, California 94710 (US)
  • LENNEN, Rebecca
    Berkeley, California 94710 (US)
  • ALIKHANI, Azadeh
    Berkeley, California 94710 (US)
  • MELIS, David
    Berkeley, California 94710 (US)
  • HELD, Mark
    Berkeley, California 94710 (US)

(74) Representative: Sagittarius IP 
Marlow International Parkway
Marlow, SL7 1YL
Marlow, SL7 1YL (GB)

   


(54) LARGE SCALE PRODUCTION OF OLIVETOL, OLIVETOLIC ACID AND OTHER ALKYL RESORCINOLS BY FERMENTATION