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EP 4 150 321 A2

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(88) Date of publication A3: 23.12.2021 (43) Date of publication: 22.03.2023 Bulletin 2023/12 (21) Application number: 21804579.7 (22) Date of filing: 13.05.2021

(51) International Patent Classification (IPC):  G01N 21/03(2006.01) G01N 27/07(2006.01) G01N 27/403(2006.01) G01N 21/05(2006.01) G01N 27/28(2006.01) G01R 1/04(2006.01) (52) Cooperative Patent Classification (CPC): G01N 33/84; B01L 2300/0663; B01L 3/5023; B01L 2200/12; B01L 2300/048; B01L 2300/042; G01N 33/48707 (86) International application number: PCT/US2021/032237 (87) International publication number: WO 2021/231718 (18.11.2021 Gazette 2021/46)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 15.05.2020 US 202063025575 P (71) Applicant: Avails Medical, Inc. Menlo Park, California 94025 (US)

(72) Inventors: BUIE, Creighton T. Daly City, California 94015 (US) RAJAN, Nitin K. Palo Alto, California 94306 (US) THEISS, Andrew H. Mountain View, California 94041 (US) PONTE, Elizabeth Botbol Menlo Park, California 94025 (US) HERGET, Meike Woodside, California 94062 (US) KNOPFMACHER, Oren S. San Francisco, California 94158 (US) LAUFER, Michael D. Menlo Park, California 94025 (US) (74) Representative: Mooser, Sebastian Thomas  Wuesthoff & Wuesthoff Patentanwälte PartG mbB Schweigerstraße 2 81541 München 81541 München (DE)