(19)

(11)

EP 4 153 180 A1

(12)

(43) Date of publication: 29.03.2023 Bulletin 2023/13 (21) Application number: 21724264.3 (22) Date of filing: 06.05.2021

(51) International Patent Classification (IPC):  A61K 31/502(2006.01) A61P 35/00(2006.01) A61K 31/517(2006.01) (52) Cooperative Patent Classification (CPC): A61K 31/517; A61K 31/502   C-Sets: A61K 31/517, A61K 31/502, A61K 2300/00; (86) International application number: PCT/EP2021/061976 (87) International publication number: WO 2021/224381 (11.11.2021 Gazette 2021/45)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 07.05.2020 US 202063021389 P (71) Applicant: Astrazeneca AB 151 85 Södertälje (SE)	(72) Inventor: TRAVERS, Jon Cambridge Cambridgeshire CB2 0AA (GB) (74) Representative: AstraZeneca Intellectual Property  Eastbrook House Shaftesbury Road Cambridge CB2 8BF Cambridge CB2 8BF (GB)