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EP 4 153 613 A1

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(43) Date of publication: 29.03.2023 Bulletin 2023/13 (21) Application number: 20936359.7 (22) Date of filing: 22.05.2020

(51) International Patent Classification (IPC):  C07K 14/545(2006.01) C07K 19/00(2006.01) A61P 3/00(2006.01) A61P 19/02(2006.01) A61K 38/20(2006.01) A61P 43/00(2006.01) A61P 3/10(2006.01) A61P 37/00(2006.01) (52) Cooperative Patent Classification (CPC): A61P 3/00; A61P 3/10; A61P 19/02; A61P 37/00; C07K 2319/30; C07K 14/7155; A61K 38/00 (86) International application number: PCT/US2020/034114 (87) International publication number: WO 2021/236091 (25.11.2021 Gazette 2021/47)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (71) Applicant: R-Pharm Overseas, Inc. La Jolla, CA 92037 (US)	(72) Inventors: LAVROVSKY, Yan Del Mar, CA 92014 (US) REPIK, Alexey Moscow, 121069 (RU) SAMSONOV, Mikhail Moscow, 025313 (RU) BARBASHOV, Sergei Irvine, CA 92603 (US) IGNATIEV, Vasily Moscow, 121353 (RU) (74) Representative: Osmans, Voldemars et al Agency Tria Robit P.O. Box 22 LV-1010 Riga LV-1010 Riga (LV)