(19)

(11)

EP 4 157 463 A1

(12)

(43) Date of publication: 05.04.2023 Bulletin 2023/14 (21) Application number: 21737121.0 (22) Date of filing: 01.06.2021

(51) International Patent Classification (IPC):  A61P 35/00(2006.01) C07D 207/12(2006.01) C07D 211/04(2006.01) C07D 217/06(2006.01) C07D 403/12(2006.01) A61K 31/40(2006.01) A61K 31/4462(2006.01) A61K 31/4025(2006.01) C07D 207/06(2006.01) C07D 209/44(2006.01) C07D 211/42(2006.01) C07D 401/12(2006.01) C07D 471/04(2006.01) A61K 31/4045(2006.01) A61K 31/4035(2006.01) A61K 31/407(2006.01) (52) Cooperative Patent Classification (CPC): C07D 207/06; C07D 207/12; C07D 211/04; C07D 211/42; C07D 209/44; C07D 471/04; C07D 403/12; C07D 401/12; C07D 217/06; A61P 35/00 (86) International application number: PCT/GB2021/051349 (87) International publication number: WO 2021/245405 (09.12.2021 Gazette 2021/49)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 01.06.2020 GB 202008201 (71) Applicant: Neophore Limited Altrincham Cheshire WA14 2DT (GB)	(72) Inventors: BLAGG, Julian London Greater London N1C 4AG (GB) ROFFEY, Jon London Greater London N1C 4AG (GB) DRYSDALE, Martin London Greater London N1C 4AG (GB) WINSHIP, Paul Walden Essex CB10 1X (GB) CLARK, David Walden Essex CB10 1X (GB) (74) Representative: HGF  HGF Limited 1 City Walk Leeds LS11 9DX Leeds LS11 9DX (GB)