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EP 4 161 547 A1

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(43) Date of publication: 12.04.2023 Bulletin 2023/15 (21) Application number: 21825822.6 (22) Date of filing: 16.06.2021

(51) International Patent Classification (IPC):  A61K 36/07(2006.01) A61K 31/4045(2006.01) B01D 11/02(2006.01) C07F 9/572(2006.01) A23L 31/00(2016.01) A61K 31/675(2006.01) C07D 209/16(2006.01) C12P 17/00(2006.01) (52) Cooperative Patent Classification (CPC): A61K 36/07; A61K 31/675; A61K 31/4045; C07F 9/572; A61P 25/00; A61K 2236/00; B01D 11/0288; B01D 11/0257; B01D 11/028; A61K 45/06; C12P 17/10 (86) International application number: PCT/CA2021/050823 (87) International publication number: WO 2021/253124 (23.12.2021 Gazette 2021/51)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 17.06.2020 US 202063040317 P 30.06.2020 US 202063046089 P 29.07.2020 CA 3088384 07.08.2020 CA 3089455 (71) Applicant: Psilio Scientific Ltd. Vancouver, BC V6R 1E3 (CA)

(72) Inventors: LIGHTBURN, Benjamin Vancouver, British Columbia V6R 1E3 (CA) MOSS, Ryan Vancouver, British Columbia V6M 1C4 (CA) RANKEN, Lisa Lake Country, British Columbia V4V 1T9 (CA) (74) Representative: Kalkoff & Partner Patentanwälte mbB  Martin-Schmeisser-Weg 3a-3b 44227 Dortmund 44227 Dortmund (DE)