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EP 4 162 035 A2

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(88) Date of publication A3: 17.03.2022 (43) Date of publication: 12.04.2023 Bulletin 2023/15 (21) Application number: 21818476.0 (22) Date of filing: 03.06.2021

(51) International Patent Classification (IPC):  C12N 9/12(2006.01) C07H 21/04(2006.01) C12P 19/34(2006.01) (52) Cooperative Patent Classification (CPC): C12N 9/1264; C12Y 207/07031; C12N 15/70; C12N 15/1034; C12P 19/34; C12Q 1/6806   C-Sets: C12Q 1/6806, C12Q 2521/131; (86) International application number: PCT/US2021/035685 (87) International publication number: WO 2021/247851 (09.12.2021 Gazette 2021/49)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 03.06.2020 US 202016891449 (71) Applicant: Molecular Assemblies Inc. San Diego, CA 92121-1514 (US)

(72) Inventors: TUBBS, Julie, L. San Diego, CA 92121 (US) SINHA, Prem San Diego, CA 92121 (US) STEC, Boguslaw San Diego, CA 92121 (US) HOLDEN, Matthew, T. San Diego, CA 92121 (US) WILSON, Christopher San Diego, CA 92121 (US) EFCAVITCH, J., William San Diego, CA 92121 (US) SAMMOND, Deanne, W. San Diego, CA 92121 (US) (74) Representative: Graham Watt & Co LLP  St. Botolph's House 7-9 St. Botolph's Road Sevenoaks TN13 3AJ Sevenoaks TN13 3AJ (GB)