(19)
(11) EP 4 164 593 A1

(12)

(43) Date of publication:
19.04.2023 Bulletin 2023/16

(21) Application number: 21727724.3

(22) Date of filing: 04.05.2021
(51) International Patent Classification (IPC): 
A61K 9/00(2006.01)
A61K 9/127(2006.01)
A61K 31/58(2006.01)
A61K 47/14(2017.01)
 A61K 9/10(2006.01)
A61K 31/4045(2006.01)
A61K 45/06(2006.01)
A61P 27/02(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 31/4045; A61K 31/58; A61K 9/1271; A61K 9/0048; A61K 47/14; A61P 27/02; A61K 45/06; A61K 9/1075; A61K 47/10; A61K 47/12; A61K 47/186
 
C-Sets:
  1. A61K 31/58, A61K 2300/00;
  2. A61K 31/4045, A61K 2300/00;
(86) International application number:
PCT/US2021/030593
(87) International publication number:
WO 2021/257193 (23.12.2021 Gazette 2021/51)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 15.06.2020 US 202063039095 P

(71) Applicants:
  • OPKO Pharmaceuticals, LLC
    Miami, FL 33137 (US)
  • Santos, Arturo
    Zapopan, Jalisco, 45116 (MX)

(72) Inventors:
  • NAVARRO, Jose
    Guadalajara, Jalisco, 44910 (MX)
  • ALTAMIRANO, Juan C.
    Guadalajara, Jalisco, 44600 (MX)
  • GONZALEZ, Alejandro
    Guadalajara, Jalisco, 44220 (MX)
  • SANTOS, Arturo
    Jalisco, 45116 (MX)

(74) Representative: Gregson, Anna Louise 
Mathys & Squire The Shard 32 London Bridge Street
London SE1 9SG
London SE1 9SG (GB)

   


(54) TRIAMCINOLONE ACETONIDE-LOADED LIPOSOMES TOPICAL OPHTHALMIC FORMULATIONS AS PRIMARY THERAPY FOR MACULAR EDEMA SECONDARY TO BRANCH RETINAL VEIN OCCLUSION