(19)

(11)

EP 4 164 750 A1

(12)

(43) Date of publication: 19.04.2023 Bulletin 2023/16 (21) Application number: 20940284.1 (22) Date of filing: 11.06.2020

(51) International Patent Classification (IPC):  A61P 35/00(2006.01) C07K 14/705(2006.01) A61P 37/02(2006.01) C07K 16/44(2006.01) A61K 39/39(2006.01) A61P 35/02(2006.01) (52) Cooperative Patent Classification (CPC): A61P 35/00; A61P 35/02; A61P 37/02; C07K 16/44; C07K 14/70575; C07K 14/70532; C07K 14/535; C07K 14/475; C07K 2319/00; C07K 2319/02; C07K 2319/03; C07K 14/7151; C07K 2317/622; C07K 2317/72; A61K 2039/5152; A61K 2039/5156; A61K 39/0011; C12N 2740/16043 (86) International application number: PCT/US2020/037283 (87) International publication number: WO 2021/251975 (16.12.2021 Gazette 2021/50)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (71) Applicant: Alloplex Biotherapeutics Woburn, MA 01801 (US)	(72) Inventor: BORRIELLO, Frank Winchester, MA 01890 (US) (74) Representative: J A Kemp LLP  80 Turnmill Street London EC1M 5QU London EC1M 5QU (GB)