(19)

(11)

EP 4 168 556 A2

(12)

(88) Date of publication A3: 21.04.2022 (43) Date of publication: 26.04.2023 Bulletin 2023/17 (21) Application number: 21748991.3 (22) Date of filing: 23.06.2021

(51) International Patent Classification (IPC):  C12N 15/67(2006.01) A61K 48/00(2006.01) (52) Cooperative Patent Classification (CPC): C12N 15/67; A61K 48/0066; C12N 15/88; C12N 2830/50 (86) International application number: PCT/US2021/038780 (87) International publication number: WO 2021/262909 (30.12.2021 Gazette 2021/52)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 23.06.2020 US 202063042822 P 23.03.2021 US 202163165094 P 24.03.2021 US 202163165469 P (71) Applicant: ModernaTX, Inc. Cambridge, MA 02139 (US)	(72) Inventors: REID, David Cambridge, MA 02139 (US) JAIN, Ruchi Cambridge, MA 02139 (US) BICKNELL, Alicia Cambridge, MA 02139 (US) KOHRER, Caroline Cambridge, MA 02139 (US) (74) Representative: Griffin, Philippa Jane et al Mathys & Squire The Shard 32 London Bridge Street London SE1 9SG London SE1 9SG (GB)