(19)
(11) EP 4 168 801 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
21.05.2025 Bulletin 2025/21

(45) Mention of the grant of the patent:
19.03.2025 Bulletin 2025/12

(21) Application number: 21742044.7

(22) Date of filing: 22.06.2021
(51) International Patent Classification (IPC): 
G01N 33/50(2006.01)
(52) Cooperative Patent Classification (CPC):
G01N 33/5091; G01N 2800/367
(86) International application number:
PCT/EP2021/066927
(87) International publication number:
WO 2021/259903 (30.12.2021 Gazette 2021/52)

(54)

SPERM STRATIFICATION

SPERMIEN-STRATIFIZIERUNG

STRATIFICATION DE SPERMATOIZOÏDES


(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR

(30) Priority: 22.06.2020 LU 101881

(43) Date of publication of application:
26.04.2023 Bulletin 2023/17

(73) Proprietor: Westfälische Wilhelms-Universität Münster
48149 Münster (DE)

(72) Inventors:
  • SCHLATT, Stefan
    48149 Münster (DE)
  • REDMANN, Klaus
    48149 Münster (DE)
  • RAUL ADRIAN, Da Costa Graterol
    48149 Münster (DE)

(74) Representative: Schiweck Weinzierl Koch Patentanwälte Partnerschaft mbB 
Ganghoferstraße 68 B
80339 München
80339 München (DE)


(56) References cited: : 
   
  • MOSKOVTSEV S. I. ET AL: "Sperm Dna Integrity: Correlation With Sperm Plasma Membrane Integrity In Semen Evaluated For Male Infertility", vol. 51, no. 1, 1 January 2005 (2005-01-01), US, pages 33 - 40, XP055783472, ISSN: 0148-5016, Retrieved from the Internet <URL:https://www.tandfonline.com/doi/pdf/10.1080/014850190512770?needAccess=true> DOI: 10.1080/014850190512770
  • MD. SHAROARE HOSSAIN ET AL: "Flow cytometry for the assessment of animal sperm integrity and functionality: state of the art", ASIAN JOURNAL OF ANDROLOGY, vol. 13, no. 3, 11 April 2011 (2011-04-11), US, pages 406 - 419, XP055292750, ISSN: 1008-682X, DOI: 10.1038/aja.2011.15
  • AL-ESSAWE ESSRAA M ET AL: "Improved cryosurvival of stallion spermatozoa after colloid centrifugation is independent of the addition of seminal plasma", CRYOBIOLOGY, ACADEMIC PRESS INC, US, vol. 81, 15 February 2018 (2018-02-15), pages 145 - 152, XP085386577, ISSN: 0011-2240, DOI: 10.1016/J.CRYOBIOL.2018.01.009
  • HERBEMONT C ET AL: "Comment choisir le spermatozoïde en ICSI ?", GYNECOLOGIE OBSTETRIQUE & FERTILITE, ELSEVIER MASSON, FR, vol. 42, no. 11, 18 September 2014 (2014-09-18), pages 800 - 805, XP029091134, ISSN: 1297-9589, DOI: 10.1016/J.GYOBFE.2014.07.030
  • MOSKOVTSEV SERGEY I ET AL: "Testicular spermatozoa have statistically significantly lower DNA damage compared with ejaculated spermatozoa in patients with unsuccessful oral antioxidant treatment", FERTILITY AND STERILITY, vol. 93, no. 4, 1 March 2010 (2010-03-01), pages 1142 - 1146, XP029105710, ISSN: 0015-0282, DOI: 10.1016/J.FERTNSTERT.2008.11.005
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).