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(11)

EP 4 171 655 A1

(12)

(43) Date of publication: 03.05.2023 Bulletin 2023/18 (21) Application number: 21829799.2 (22) Date of filing: 25.06.2021

(51) International Patent Classification (IPC):  A61K 47/68(2017.01) A61P 37/00(2006.01) C07K 16/28(2006.01) A61P 35/00(2006.01) A61P 29/00(2006.01) (52) Cooperative Patent Classification (CPC): A61P 29/00; A61P 37/00; A61P 35/00; A61K 47/6831; A61K 47/6803; A61K 47/6889; A61K 47/6809; A61K 47/6849; C07K 16/2827; C07K 2317/522; C07K 2317/524; C07K 2317/21; C07K 2317/92; C07K 2317/622; A61K 2039/505 (86) International application number: PCT/IB2021/000445 (87) International publication number: WO 2021/260438 (30.12.2021 Gazette 2021/52)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 26.06.2020 US 202063044764 P (71) Applicants: Intocell, Inc. Daedeok-gu Daejeon 34324 (KR) Y-Biologics Inc. Daejeon 34014 (KR)

(72) Inventors: PARK, Taekyo Daejeon 34324 (KR) KIM, Sunyoung Daejeon 34324 (KR) PARK, Suho Daejeon 34324 (KR) JUNG, Doohwan Daejeon 34324 (KR) SEO, Donghoon Daejeon 34324 (KR) LEE, Sangkwang Daejeon 34324 (KR) YUN, Sanghyeon Daejeon 34324 (KR) HA, Jihyeon Daejeon 34324 (KR) LEE, Hyang, Sook Daejeon 34324 (KR) PARK, Okku Daejeon 34324 (KR) SEO, Beomseok Daejeon 34324 (KR) KIM, Sena Daejeon 34324 (KR) SEOL, Minah Daejeon 34324 (KR) SONG, Jina Daejeon 34324 (KR) WOO, Sung, Ho Daejeon 34324 (KR) CHO, Jongun Daejeon 34324 (KR) LEE, Jaeho Daejeon 34324 (KR) LEE, Hyun, Mi Daejeon 34013 (KR) PARK, Jae, Eun Daejeon 34013 (KR) SONG, Youngja Daejeon 34013 (KR) LEE, Eunjin Daejeon 34013 (KR) LEE, Hyun Ju Daejeon 34013 (KR) SHIM, Eun-Young Daejeon 34013 (KR) KO, Yunjung Daejeon 34013 (KR) LEE, Minju Daejeon 34013 (KR) PARK, Young, Woo Daejeon 34013 (KR) REW, Yosup Daejeon 34324 (KR) (74) Representative: HGF  HGF Limited 1 City Walk Leeds LS11 9DX Leeds LS11 9DX (GB)