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(11)

EP 4 178 560 A1

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(43) Date of publication: 17.05.2023 Bulletin 2023/20 (21) Application number: 21838077.2 (22) Date of filing: 08.07.2021

(51) International Patent Classification (IPC):  A61K 31/165(2006.01) C07F 9/32(2006.01) C07C 323/62(2006.01) (52) Cooperative Patent Classification (CPC): A61K 31/165; C07D 211/46; C07D 211/48; C07C 323/52; C07C 323/60; C07C 53/18; C07D 205/12; C07D 207/12 (86) International application number: PCT/US2021/040940 (87) International publication number: WO 2022/011174 (13.01.2022 Gazette 2022/02)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 08.07.2020 US 202063049615 P 11.11.2020 US 202063112444 P (71) Applicant: Klotho Therapeutics, Inc. Las Vegas, Nevada 89109 (US)	(72) Inventors: PLANTE, James Las Vegas, Nevada 89109 (US) RAMAGE, William Del Mar, California 92014 (US) SMITH, Christopher San Diego, California 92130 (US) BISHOP, Michael San Diego, California 92128 (US) (74) Representative: Lee, Nicholas John et al Kilburn & Strode LLP Lacon London 84 Theobalds Road London WC1X 8NL London WC1X 8NL (GB)