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(11)

EP 4 188 447 A1

(12)

(43) Date of publication: 07.06.2023 Bulletin 2023/23 (21) Application number: 20947059.0 (22) Date of filing: 29.07.2020

(51) International Patent Classification (IPC):  A61K 47/50(2017.01) A61K 47/54(2017.01) (52) Cooperative Patent Classification (CPC): A61K 47/55; C07D 471/04; C07D 519/00 (86) International application number: PCT/US2020/044043 (87) International publication number: WO 2022/025880 (03.02.2022 Gazette 2022/05)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (71) Applicant: Foghorn Therapeutics Inc. Cambridge MA 02142 (US)	(72) Inventors: RUPPEL, Sabine, K. Cambridge, MA 02142 (US) YANG, Zhaoxia Cambridge, MA 02142 (US) LOWE, Jason, T. Cambridge, MA 02142 (US) VOIGT, Johannes, H. Cambridge, MA 02142 (US) NETHERTON, Matthew Cambridge, MA 02142 (US) BRUCELLE, Francois Cambridge, MA 02142 (US) (74) Representative: Carpmaels & Ransford LLP  One Southampton Row London WC1B 5HA London WC1B 5HA (GB)