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(11)

EP 4 188 959 A1

(12)

(43) Date of publication: 07.06.2023 Bulletin 2023/23 (21) Application number: 21850106.2 (22) Date of filing: 27.07.2021

(51) International Patent Classification (IPC):  C07K 16/28(2006.01) C07K 14/71(2006.01) C07K 16/30(2006.01) A61P 35/00(2006.01) (52) Cooperative Patent Classification (CPC): A61P 35/00; C07K 16/3092; C07K 2317/34; C07K 2317/622; C07K 2317/73; A61K 2039/505; C07K 14/7051; C07K 2319/03; C07K 2319/33 (86) International application number: PCT/US2021/071017 (87) International publication number: WO 2022/027039 (03.02.2022 Gazette 2022/05)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 29.07.2020 US 202063058044 P 07.12.2020 US 202063122234 P 19.02.2021 US 202163151380 P 09.04.2021 US 202163173083 P 05.05.2021 US 202163184724 P (71) Applicant: Minerva Biotechnologies Corporation Waltham, MA 02451 (US)

(72) Inventors: BAMDAD, Cynthia Waltham, Massachusetts 02451 (US) SMAGGHE, Benoit Waltham, Massachusetts 02451 (US) (74) Representative: Mewburn Ellis LLP  Aurora Building Counterslip Bristol BS1 6BX Bristol BS1 6BX (GB)