(19)
(11) EP 4 196 139 A2

(12)

(88) Date of publication A3:
14.04.2022

(43) Date of publication:
21.06.2023 Bulletin 2023/25

(21) Application number: 21778590.6

(22) Date of filing: 12.08.2021
(51) International Patent Classification (IPC): 
A61K 35/74(2015.01)
A61K 38/18(2006.01)
A61K 38/20(2006.01)
A61P 35/00(2006.01)
C12N 1/20(2006.01)
C12N 15/63(2006.01)
A61P 37/04(2006.01)
 A61K 38/17(2006.01)
A61K 38/19(2006.01)
A61K 39/00(2006.01)
C07K 16/28(2006.01)
C12N 15/09(2006.01)
A61K 48/00(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 35/74; A61K 38/2013; A61K 38/208; A61K 38/20; A61K 38/191; A61K 38/19; A61K 38/1841; A61K 38/2086; C07K 16/2818; A61K 39/0011; A61P 35/00; A61K 38/1709; A61K 48/00; A61P 37/04; C07K 16/1235; C07K 16/2809; C07K 16/2803; C07K 2317/31; C07K 2317/622; C07K 2317/76; C07K 2317/52; A61K 39/39558; C07K 16/28; C12N 9/1007; C12Y 201/01045; C12N 1/20; A61K 2039/5156; A61K 39/39; A61K 2039/522; A61K 2039/523; A61K 39/12; A61K 2039/53; A61K 2039/55533; A61K 2039/55522; C12N 15/64; C12N 15/74; C12N 15/70; C07K 14/255; C07K 14/56; C07K 14/565; C07K 2319/43; C07K 14/54; C07K 14/5434; C07K 14/4705; C07K 14/4748
 
C-Sets:
A61K 39/39558, A61K 2300/00;
(86) International application number:
PCT/US2021/045832
(87) International publication number:
WO 2022/036159 (17.02.2022 Gazette 2022/07)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 12.08.2020 US 202063064869 P
13.05.2021 US 202163188443 P
13.05.2021 US 202117320200

(71) Applicant: Actym Therapeutics, Inc.
Berkeley, CA 94710 (US)

(72) Inventors:
  • GLICKMAN, Laura, Hix
    Oakland, CA 94611 (US)
  • PETERSON, Bret, Nicholas
    Oakland, CA 94602 (US)
  • KEHOE, Haixing
    Berkeley, CA 94709 (US)
  • IANNELLO, Alexandre, Charles Michel
    Oakland, CA 94618 (US)
  • THANOS, Christopher, D.
    Tiburon, CA 94920 (US)

(74) Representative: Hoffmann Eitle 
Patent- und Rechtsanwälte PartmbB Arabellastraße 30
81925 München
81925 München (DE)

   


(54) IMMUNOSTIMULATORY BACTERIA-BASED VACCINES, THERAPEUTICS, AND RNA DELIVERY PLATFORMS