(19)
(11) EP 4 196 151 A1

(12)

(43) Date of publication:
21.06.2023 Bulletin 2023/25

(21) Application number: 21778257.2

(22) Date of filing: 13.08.2021
(51) International Patent Classification (IPC): 
A61K 39/00(2006.01)
C07K 14/725(2006.01)
A61K 31/519(2006.01)
A61K 31/454(2006.01)
A61P 35/00(2006.01)
C07K 14/705(2006.01)
A61K 45/06(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 39/0012; A61K 2039/892; A61P 35/00; C07K 14/7051; C07K 14/705; C07K 2319/03; A61K 39/001102; A61K 45/06; A61K 31/454; A61K 31/502; A61K 31/5025; A61K 31/4184; A61K 31/55
 
C-Sets:
  1. A61K 31/5025, A61K 2300/00;
  2. A61K 31/4184, A61K 2300/00;
  3. A61K 31/55, A61K 2300/00;
  4. A61K 39/001102, A61K 2300/00;
  5. A61K 39/0012, A61K 2300/00;
  6. A61K 31/454, A61K 2300/00;
  7. A61K 31/502, A61K 2300/00;

(86) International application number:
PCT/US2021/046041
(87) International publication number:
WO 2022/036285 (17.02.2022 Gazette 2022/07)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 14.08.2020 US 202063066150 P
02.10.2020 US 202063087049 P
28.07.2021 US 202163226712 P

(71) Applicants:
  • Cero Therapeutics, Inc.
    South San Francisco, CA 94080 (US)
  • Corey, Daniel Mark
    Menlo Park, CA 94025 (US)
  • Kipniss, Nathan
    South San Francisco, California 94080 (US)
  • O'Donoghue, Geoff
    South San Francisco, California 94080 (US)

(72) Inventors:
  • COREY, Daniel Mark
    Menlo Park, California 94025 (US)
  • KIPNISS, Nathan
    San Francisco, California 94080 (US)
  • O'DONOGHUE, Geoff
    San Francisco, California 94080 (US)

(74) Representative: Hoffmann Eitle 
Patent- und Rechtsanwälte PartmbB Arabellastraße 30
81925 München
81925 München (DE)

   


(54) COMPOSITIONS AND METHODS FOR TREATING CANCER WITH CHIMERIC TIM RECEPTORS IN COMBINATION WITH INHIBITORS OF POLY (ADP-RIBOSE) POLYMERASE