(19)
(11) EP 4 199 965 A1

(12)

(43) Date of publication:
28.06.2023 Bulletin 2023/26

(21) Application number: 21857698.1

(22) Date of filing: 18.08.2021
(51) International Patent Classification (IPC): 
A61K 39/395(2006.01)
A61K 47/18(2017.01)
A61P 29/00(2006.01)
A61K 9/08(2006.01)
A61P 19/02(2006.01)
(52) Cooperative Patent Classification (CPC):
A61P 29/00; A61P 19/02; A61K 9/08; A61K 9/0019; A61K 47/12; A61K 47/183; A61K 47/26; C07K 2317/76; C07K 2317/24; A61K 39/39591; C07K 16/2866
(86) International application number:
PCT/CN2021/113241
(87) International publication number:
WO 2022/037606 (24.02.2022 Gazette 2022/08)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 19.08.2020 WO PCT/CN2020/109965

(71) Applicant: Bio-Thera Solutions, Ltd.
Guangzhou, Guangdong 510530 (CN)

(72) Inventors:
  • WU, Zhihao
    Guangzhou, Guangdong 510530 (CN)
  • WU, Yong
    Guangzhou, Guangdong 510530 (CN)
  • CHEN, Yanyu
    Guangzhou, Guangdong 510530 (CN)
  • HUANG, Dandan
    Guangzhou, Guangdong 510530 (CN)
  • LUO, Xiaoping
    Guangzhou, Guangdong 510530 (CN)
  • ZHENG, Kun
    Guangzhou, Guangdong 510530 (CN)
  • LI, Qingrui
    Guangzhou, Guangdong 510530 (CN)
  • YANG, Yili
    Guangzhou, Guangdong 510530 (CN)
  • LIU, Yujie
    Guangzhou, Guangdong 510530 (CN)
  • LIU, Cuihua
    Guangzhou, Guangdong 510530 (CN)
  • LI, Shengfeng
    Guangzhou, Guangdong 510530 (CN)

(74) Representative: Elkington and Fife LLP 
Prospect House 8 Pembroke Road
Sevenoaks, Kent TN13 1XR
Sevenoaks, Kent TN13 1XR (GB)

   


(54) LIQUID FORMULATIONS COMPRISING HIGH CONCENTRATIONS HUMANIZED ANTIBODIES FOR TREATING IL-6 RELATED DISEASES