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EP 4 204 004 A1

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(43) Date of publication: 05.07.2023 Bulletin 2023/27 (21) Application number: 21862987.1 (22) Date of filing: 31.08.2021

(51) International Patent Classification (IPC):  A61K 39/395(2006.01) C07K 16/00(2006.01) C07K 16/28(2006.01) A61K 51/00(2006.01) C07K 16/24(2006.01) (52) Cooperative Patent Classification (CPC): C07K 16/2863; C07K 16/4208; C07K 2317/622; C07K 2317/21; C07K 14/7051; C12N 15/62 (86) International application number: PCT/US2021/048532 (87) International publication number: WO 2022/047417 (03.03.2022 Gazette 2022/09)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 31.08.2020 WO PCT/US2020/048843 11.01.2021 US 202163136177 P 01.03.2021 US 202163200329 P 04.03.2021 WO PCT/US2021/020922 (71) Applicant: EXUMA BIOTECH CORP. West Palm Beach, FL 33401 (US)

(72) Inventors: FROST, Gregory Ian Palm Beach, FL 33401 (US) SCHREIBER, Gregory Harold Palm Beach, FL 33401 (US) KUNDU, Anirban Palm Beach, FL 33401 (US) (74) Representative: Turner, Craig Robert et al AA Thornton IP LLP Octagon Point 5 Cheapside London EC2V 6AA London EC2V 6AA (GB)