(19)

(11)

EP 4 204 023 A1

(12)

(43) Date of publication: 05.07.2023 Bulletin 2023/27 (21) Application number: 21883454.7 (22) Date of filing: 20.10.2021

(51) International Patent Classification (IPC):  A61L 2/10(2006.01) A61L 2/18(2006.01) (52) Cooperative Patent Classification (CPC): A61L 2/10; A61L 2202/122; A61L 2202/14; A61L 2202/16 (86) International application number: PCT/TR2021/051072 (87) International publication number: WO 2022/086478 (28.04.2022 Gazette 2022/17)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 21.10.2020 TR 202016775 (71) Applicant: Dokuz Eylul Üniversitesi Rektorlugu 35220 Konak/Izmir (TR)	(72) Inventors: ÖZEL DEM RALP, Fatma Duygu 06830 Gölba i/Ankara (TR) AKINCI, Görkem 35510 Bayrakli/ zmir (TR) AKINCI, Metin 35510 Bayrakli/ zmir (TR)