(19)

(11)

EP 4 204 448 A2

(12)

(88) Date of publication A3: 16.06.2022 (43) Date of publication: 05.07.2023 Bulletin 2023/27 (21) Application number: 21769136.9 (22) Date of filing: 27.08.2021

(51) International Patent Classification (IPC):  C07K 16/18(2006.01) A61K 39/00(2006.01) C07K 16/28(2006.01) A61P 35/00(2006.01) (52) Cooperative Patent Classification (CPC): C07K 16/18; C07K 16/28; A61K 39/0011; A61K 2039/6056; C12N 2710/20034; A61P 35/00; C07K 2317/622; C07K 2317/31; C07K 2317/52; C07K 2317/77 (86) International application number: PCT/EP2021/073781 (87) International publication number: WO 2022/043517 (03.03.2022 Gazette 2022/09)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 27.08.2020 EP 20193168 (71) Applicants: cureab GmbH 4125 Riehen (CH) Universität Basel Vizerektorat Forschung 4001 Basel (CH)	(72) Inventors: STENNER-LIEWEN, Frank 4125 Riehen (CH) MARKULY, Norbert 5080 Laufenburg (CH) LIEWEN, Heike 4125 Riehen (CH) LIU, Yang 5073 Gipf-Oberfrick (CH) (74) Representative: Vossius & Partner Patentanwälte Rechtsanwälte mbB  Siebertstraße 3 81675 München 81675 München (DE)