(19)

(11)

EP 4 208 080 A1

(12)

(43) Date of publication: 12.07.2023 Bulletin 2023/28 (21) Application number: 21865231.1 (22) Date of filing: 03.09.2021

(51) International Patent Classification (IPC):  A61B 5/00(2006.01) (52) Cooperative Patent Classification (CPC): A61B 5/4839; A61B 5/021; A61B 5/024; A61B 5/7275 (86) International application number: PCT/US2021/049160 (87) International publication number: WO 2022/051678 (10.03.2022 Gazette 2022/10)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 04.09.2020 US 202063074805 P (71) Applicant: Cedars-Sinai Medical Center Los Angeles, CA 90048 (US)	(72) Inventor: KHANDWALLA, Raj Santa Monica, California 90405 (US) (74) Representative: Pitchford, James Edward et al Mathys & Squire The Shard 32 London Bridge Street London SE1 9SG London SE1 9SG (GB)