(19)
(11) EP 4 208 479 A1

(12)

(43) Date of publication:
12.07.2023 Bulletin 2023/28

(21) Application number: 21865212.1

(22) Date of filing: 03.09.2021
(51) International Patent Classification (IPC): 
C07K 16/10(2006.01)
(52) Cooperative Patent Classification (CPC):
C07K 16/10; C07K 2317/21; C07K 2317/76; C07K 2317/92; C07K 2317/33; A61K 2039/505; C07K 2317/56; A61K 2039/544; C07K 2317/30; A61K 2039/507
(86) International application number:
PCT/US2021/049112
(87) International publication number:
WO 2022/051650 (10.03.2022 Gazette 2022/10)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 03.09.2020 US 202063074207 P

(71) Applicants:
  • The UAB Research Foundation
    Birmingham, AL 35294 (US)
  • Texas Biomedical Research Institute
    San Antonio, TX 78227 (US)

(72) Inventors:
  • KOBIE, James
    Birmingham, AL 35242 (US)
  • WALTER, Mark R.
    Vestavia Hills, AL 35243 (US)
  • PIEPENBRINK, Michael
    Birmingham, AL 35294 (US)
  • DESHPANDE, Ashlesha
    Vestavia Hills, AL 35216 (US)
  • GOPEFERT, Paul
    Birmingham, AL 35294 (US)
  • ERDMANN, Nathaniel
    Birmingham, AL 35294 (US)
  • MARTINEZ-SOBRIDO, Luis
    San Antonio, TX 78212 (US)
  • BASU, Madhubanti
    Birmingham, AL 35294 (US)
  • SARKAR, Sanghita
    Homewood, AL 35209 (US)
  • OLADUNNI, Fatai
    San Antonio, TX 78251 (US)
  • PARK, Jun-Gyu
    San Antonio, TX 78245 (US)

(74) Representative: Bryers LLP 
Bristol & Bath Science Park Dirac Crescent, Emerson's Green
Bristol, BS16 7FR
Bristol, BS16 7FR (GB)

   


(54) HUMAN MONOCLONAL ANTIBODIES TO SARS-COV-2 AND USE THEREOF