(19)

(11)

EP 4 213 866 A1

(12)

(43) Date of publication: 26.07.2023 Bulletin 2023/30 (21) Application number: 21870007.8 (22) Date of filing: 09.09.2021

(51) International Patent Classification (IPC):  A61K 38/01(2006.01) A61K 8/65(2006.01) A61K 38/39(2006.01) (52) Cooperative Patent Classification (CPC): C07K 14/78; A61K 38/00 (86) International application number: PCT/US2021/049646 (87) International publication number: WO 2022/060622 (24.03.2022 Gazette 2022/12)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 16.09.2020 US 202063079187 P 19.10.2020 US 202063093554 P 12.02.2021 US 202163149068 P (71) Applicant: Collagen Matrix, Inc. Oakland, NJ 07436 (US)	(72) Inventors: LEE, Natsuyo Shishido Basking Ridge, New Jersey 07920 (US) AMMON, Daniel New York 14580 (US) CHEN, Hui-Chen Wayne, New Jersey 07470 (US) (74) Representative: Haseltine Lake Kempner LLP  Cheapside House 138 Cheapside London EC2V 6BJ London EC2V 6BJ (GB)