(19)

(11)

EP 4 214 242 A1

(12)

(43) Date of publication: 26.07.2023 Bulletin 2023/30 (21) Application number: 21789967.3 (22) Date of filing: 15.09.2021

(51) International Patent Classification (IPC):  C07K 16/40(2006.01) A61P 7/10(2006.01) C07K 16/10(2006.01) A61P 31/14(2006.01) (52) Cooperative Patent Classification (CPC): C07K 16/40; C07K 2319/02; C07K 2319/50; C12N 2799/022; C12N 2840/007; C12N 2800/22; C12N 2830/008; A61K 2039/505; C12N 2750/14141; C07K 16/10; A61P 31/14; A61P 7/10 (86) International application number: PCT/US2021/050565 (87) International publication number: WO 2022/060916 (24.03.2022 Gazette 2022/12)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 15.09.2020 US 202063078865 P 28.10.2020 US 202063106848 P (71) Applicant: RegenxBio Inc. Rockville, MD 20850 (US)	(72) Inventors: LIU, Ye Rockville, MD 20850 (US) BRUDER, Joseph Rockville, MD 20850 (US) MCDOUGALD, Devin Rockville, MD 20850 (US) (74) Representative: Appleyard Lees IP LLP  15 Clare Road Halifax HX1 2HY Halifax HX1 2HY (GB)