(19)
(11) EP 4 222 272 A1

(12)

(43) Date of publication:
09.08.2023 Bulletin 2023/32

(21) Application number: 21778512.0

(22) Date of filing: 29.09.2021
(51) International Patent Classification (IPC): 
C12N 15/861(2006.01)
C12N 15/87(2006.01)
(52) Cooperative Patent Classification (CPC):
C12N 15/86; C12N 2710/10343; C12N 2710/10351; C12N 2710/10345; C12N 2310/20
(86) International application number:
PCT/EP2021/076757
(87) International publication number:
WO 2022/069523 (07.04.2022 Gazette 2022/14)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 29.09.2020 EP 20198944

(71) Applicant: Albert-Ludwigs-Universität Freiburg
79098 Freiburg (DE)

(72) Inventors:
  • RUZSICS, Zsolt
    86911 Dießen am Ammersee (DE)
  • RIEDL, André
    79089 Freiburg (DE)
  • FISCHER, Julian
    79106 Freiburg (DE)
  • BURGERT, Hans-Gerhard
    79819 Bad Krozingen (DE)

(74) Representative: Hertin und Partner Rechts- und Patentanwälte PartG mbB 
Kurfürstendamm 54/55
10707 Berlin
10707 Berlin (DE)

   


(54) RESCUE OF RECOMBINANT ADENOVIRUSES BY CRISPR/CAS-MEDIATED IN VIVO TERMINAL RESOLUTION