(19)
(11) EP 4 232 451 A1

(12)

(43) Date of publication:
30.08.2023 Bulletin 2023/35

(21) Application number: 21882228.6

(22) Date of filing: 22.10.2021
(51) International Patent Classification (IPC): 
C07D 487/04(2006.01)
A61K 31/5377(2006.01)
A61P 29/00(2006.01)
A61K 31/519(2006.01)
A61P 27/02(2006.01)
(52) Cooperative Patent Classification (CPC):
C07D 487/04; A61P 29/00; A61P 27/02; A61P 17/00; A61P 17/06; A61P 11/00; C07D 519/00
(86) International application number:
PCT/IB2021/000710
(87) International publication number:
WO 2022/084741 (28.04.2022 Gazette 2022/17)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 23.10.2020 US 202063104979 P

(71) Applicant: Ildong Pharmaceutical Co., Ltd.
Seoul 06752 (KR)

(72) Inventors:
  • LEE, Myongjae
    Hwaseong-si Gyeonggi-do 18449 (KR)
  • OH, Changmok
    Hwaseong-si Gyeonggi-do 18449 (KR)
  • LIM, Dami
    Hwaseong-si Gyeonggi-do 18449 (KR)
  • KIM, Kyeong-a
    Hwaseong-si Gyeonggi-do 18449 (KR)
  • LEE, Seolhee
    Hwaseong-si Gyeonggi-do 18449 (KR)
  • JEONG, Ilji
    Hwaseong-si Gyeonggi-do 18449 (KR)
  • RYU, Jaeeun
    Hwaseong-si Gyeonggi-do 18449 (KR)
  • LEE, Jooyun
    Hwaseong-si Gyeonggi-do 18449 (KR)
  • JUN, Yearin
    Hwaseong-si Gyeonggi-do 18449 (KR)
  • KWON, Jinsun
    Hwaseong-si Gyeonggi-do 18449 (KR)
  • SOHN, Te-ik
    Hwaseong-si Gyeonggi-do 18449 (KR)
  • KIM, Gunhee
    Hwaseong-si Gyeonggi-do 18449 (KR)
  • KIM, Jungho
    Hwaseong-si Gyeonggi-do 18449 (KR)
  • YOON, Jongmin
    Hwaseong-si Gyeonggi-do 18449 (KR)
  • LEE, Jin Hee
    Hwaseong-si Gyeonggi-do 18449 (KR)
  • YOON, Hongchul
    Hwaseong-si Gyeonggi-do 18449 (KR)
  • LEE, Jung Woo
    Hwaseong-si Gyeonggi-do 18449 (KR)
  • PARK, Joontae
    Hwaseong-si Gyeonggi-do 18449 (KR)
  • AN, Kyung Mi
    Hwaseong-si Gyeonggi-do 18449 (KR)

(74) Representative: Engelhard, Markus 
Boehmert & Boehmert Anwaltspartnerschaft mbB Pettenkoferstrasse 22
80336 München
80336 München (DE)

   


(54) CFTR MODULATOR COMPOUNDS, COMPOSITIONS, AND USES THEREOF