(19)

(11)

EP 4 232 596 A1

(12)

(43) Date of publication: 30.08.2023 Bulletin 2023/35 (21) Application number: 21802597.1 (22) Date of filing: 20.10.2021

(51) International Patent Classification (IPC):  C12Q 1/68(2018.01) C12N 15/10(2006.01) C12Q 1/70(2006.01) (52) Cooperative Patent Classification (CPC): C12N 15/1003; C12Q 1/70; C12Q 1/701; C12Q 1/6806   C-Sets: C12Q 1/6806, C12Q 2527/125; C12Q 1/70, C12Q 2521/107, C12Q 2531/113; (86) International application number: PCT/EP2021/079071 (87) International publication number: WO 2022/084381 (28.04.2022 Gazette 2022/17)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 20.10.2020 GB 202016650 (71) Applicant: Primer Design Ltd Camberley, Surrey GU15 3AD (GB)	(72) Inventors: ANDERSON, Stephanie Camberley Surrey GU15 3AD (GB) ARANCONGARCIA, David Camberley Surrey GU15 3AD (GB) OLADIMEJI, Paul Camberley Surrey GU15 3AD (GB) (74) Representative: Greaves Brewster LLP  Copa House Station Road Cheddar, Somerset BS27 3AH Cheddar, Somerset BS27 3AH (GB)