(19)

(11)

EP 4 240 406 A1

(12)

(43) Date of publication: 13.09.2023 Bulletin 2023/37 (21) Application number: 21816264.2 (22) Date of filing: 05.11.2021

(51) International Patent Classification (IPC):  A61K 39/00(2006.01) C07K 16/28(2006.01) A61P 35/02(2006.01) (52) Cooperative Patent Classification (CPC): C07K 16/2809; C07K 16/2803; C07K 2317/73; C07K 2317/31; A61P 35/02; C07K 16/2818; C07K 2317/76; C07K 2317/24; A61K 2039/505; A61K 2039/507; C07K 2317/626; C07K 2317/75 (86) International application number: PCT/US2021/058254 (87) International publication number: WO 2022/099006 (12.05.2022 Gazette 2022/19)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 05.11.2020 US 202063110011 P (71) Applicant: Anji Bruno, LLC Cambridge, MA 02142 (US)	(72) Inventors: SMITH, Victoria South San Francisco, California 94080 (US) SARDE, Aurelien Palo Alto, California 94306 (US) (74) Representative: HGF  HGF Limited 1 City Walk Leeds LS11 9DX Leeds LS11 9DX (GB)