(19)
(11) EP 4 240 415 A1

(12)

(43) Date of publication:
13.09.2023 Bulletin 2023/37

(21) Application number: 21816258.4

(22) Date of filing: 05.11.2021
(51) International Patent Classification (IPC): 
A61K 39/395(2006.01)
A61K 33/243(2019.01)
A61P 35/00(2006.01)
C07K 16/28(2006.01)
C07K 16/42(2006.01)
A61K 31/00(2006.01)
A61K 47/68(2017.01)
A61P 35/02(2006.01)
C07K 16/32(2006.01)
A61K 39/00(2006.01)
(52) Cooperative Patent Classification (CPC):
C07K 16/42; C07K 2317/72; C07K 16/2878; C07K 2317/73; C07K 16/32; C07K 2317/24; A61K 39/39541; A61K 2039/507; C07K 2317/41; A61P 35/02; A61K 2039/505; A61P 35/00; C07K 2317/71; C07K 16/2803; C07K 16/2875; A61K 47/6849; A61K 47/6851; A61K 47/6803; A61K 31/40; A61K 31/535
(86) International application number:
PCT/US2021/058208
(87) International publication number:
WO 2022/098972 (12.05.2022 Gazette 2022/19)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 08.11.2020 US 202063111045 P
08.04.2021 US 202163172411 P
08.06.2021 US 202163208179 P

(71) Applicant: Seagen Inc.
Bothell, WA 98021 (US)

(72) Inventors:
  • GARDAI, Shyra
    Bothell, Washington 98021 (US)
  • SMITH, Alyson
    Bothell, Washington 98021 (US)
  • KLUSSMAN, Kerry
    Bothell, Washington 98021 (US)
  • LIU, Bernard
    Bothell, Washington 98021 (US)
  • VAN EPPS, Heather
    Bothell, Washington 98021 (US)

(74) Representative: J A Kemp LLP 
80 Turnmill Street
London EC1M 5QU
London EC1M 5QU (GB)

   


(54) COMBINATION-THERAPY ANTIBODY DRUG CONJUGATE WITH IMMUNE CELL INHIBITOR