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(11)

EP 4 244 249 A1

(12)

(43) Date of publication: 20.09.2023 Bulletin 2023/38 (21) Application number: 21820754.6 (22) Date of filing: 09.11.2021

(51) International Patent Classification (IPC):  C07K 16/18(2006.01) A61K 39/00(2006.01) C07K 16/28(2006.01) (52) Cooperative Patent Classification (CPC): C07K 16/2881; A61K 2039/505; C07K 2317/569; C07K 2317/92; C07K 2317/52; C07K 2317/71; C07K 2317/33; C07K 2317/77 (86) International application number: PCT/US2021/058661 (87) International publication number: WO 2022/103769 (19.05.2022 Gazette 2022/20)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 11.11.2020 US 202063112314 P 17.08.2021 US 202163234210 P (71) Applicant: Ossianix Inc. Philadelphia, PA 19104 (US)

(72) Inventors: STOCKI, Pawel Royston Hertfordshire SG8 5DU (GB) SZARY, Jaroslaw Michal Cambridge CB1 7SP (GB) WICHER, Krzysztof Bartlomiej Cambridge CB5 8ZS (GB) THEI, Laura Cambridge CB1 3BU (GB) RUTKOWSKI, Julia Lynn Bryn Mawr, Pennsylvania 19010 (US) DEMYDCHUK, Mykhaylo Cambridge CB1 9GR (GB) COKER, Shu-Fen Amersham HP6 6LW (GB) (74) Representative: Inspicos P/S  Agern Allé 24 2970 Hørsholm 2970 Hørsholm (DK)