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EP 4 247 430 A1

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(43) Date of publication: 27.09.2023 Bulletin 2023/39 (21) Application number: 21895766.0 (22) Date of filing: 22.11.2021

(51) International Patent Classification (IPC):  A61K 47/64(2017.01) C07K 14/47(2006.01) A61K 51/08(2006.01) A61K 39/395(2006.01) (52) Cooperative Patent Classification (CPC): C07K 16/32; A61P 35/00; A61K 39/39558; C07K 16/2803; A61K 2039/507; A61K 51/1021; A61K 51/1045; A61K 51/1093; A61K 51/1096; A61K 45/06   C-Sets: A61K 39/39558, A61K 2300/00; (86) International application number: PCT/US2021/060370 (87) International publication number: WO 2022/109404 (27.05.2022 Gazette 2022/21)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 20.11.2020 US 202063116225 P 25.11.2020 US 202063118181 P 28.07.2021 US 202163226699 P 30.09.2021 US 202163250725 P 22.10.2021 WO PCT/US2021/056259 (71) Applicant: Actinium Pharmaceuticals, Inc. New York, NY 10017 (US)

(72) Inventors: LUDWIG, Dale L Rockaway, New Jersey 07866 (US) GEOGHEGAN, Eileen Mamaroneck, New York 10543 (US) SETH, Sandesh New York, New York 10016 (US) DIAMOND, Paul Fort Lee, New Jersey 07024 (US) (74) Representative: Forresters IP LLP  Skygarden Erika-Mann-Straße 11 80636 München 80636 München (DE)