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EP 4 251 633 A1

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(43) Date of publication: 04.10.2023 Bulletin 2023/40 (21) Application number: 21896011.0 (22) Date of filing: 25.11.2021

(51) International Patent Classification (IPC):  C07H 19/20(2006.01) A61P 35/00(2006.01) A61K 31/7076(2006.01) (52) Cooperative Patent Classification (CPC): A61P 35/00; C07H 19/20; A61K 45/06 (86) International application number: PCT/CA2021/051688 (87) International publication number: WO 2022/109741 (02.06.2022 Gazette 2022/22)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 25.11.2020 CN 202011346141 23.12.2020 US 202017133348 (71) Applicant: Risen (Suzhou) Pharma Tech Co., Ltd. Suzhou, Jiangsu 215123 (CN)

(72) Inventors: ZHANG, Yuhua Suzhou, Jiangsu 215000 (CN) HUANG, Chuanhao Suzhou, Jiangsu 215000 (CN) KONG, Xianqi Dollard-des-Ormeaux, Québec H9B 3J7 (CA) CHEN, Gang Suzhou, Jiangsu 215000 (CN) LU, Jiasheng Shanghai 201702 (CN) ZHANG, Qiguo Suzhou, Jiangsu 215000 (CN) CHEN, Dawei Suzhou, Jiangsu 215000 (CN) ZHU, Xingwu Suzhou, Jiangsu 215000 (CN) (74) Representative: Høiberg P/S  Adelgade 12 1304 Copenhagen K 1304 Copenhagen K (DK)