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EP 4 251 770 A1

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(43) Date of publication: 04.10.2023 Bulletin 2023/40 (21) Application number: 22750549.2 (22) Date of filing: 07.02.2022

(51) International Patent Classification (IPC):  C12Q 1/6874(2018.01) C12Q 1/686(2018.01) C12Q 1/68(2018.01) C12Q 1/6869(2018.01) C12Q 1/6806(2018.01) C12N 15/10(2006.01) (52) Cooperative Patent Classification (CPC): C12Q 1/6869   C-Sets: C12Q 1/6869, C12Q 2535/119, C12Q 2535/122, C12Q 2565/518; (86) International application number: PCT/US2022/015527 (87) International publication number: WO 2022/170212 (11.08.2022 Gazette 2022/32)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 08.02.2021 US 202163147167 P 19.03.2021 US 202163163638 P 03.05.2021 US 202163183585 P (71) Applicant: Singular Genomics Systems, Inc. San Diego, CA 92121 (US)

(72) Inventors: WITTERS, Daan San Diego, California 92121 (US) GLEZER, Eli, N. San Diego, California 92121 (US) LIPSON, Allen San Diego, California 92121 (US) (74) Representative: Wichmann, Hendrik  Wuesthoff & Wuesthoff Patentanwälte PartG mbB Schweigerstraße 2 81541 München 81541 München (DE)