(19)
(11) EP 4 255 896 A1

(12)

(43) Date of publication:
11.10.2023 Bulletin 2023/41

(21) Application number: 21823828.5

(22) Date of filing: 30.11.2021
(51) International Patent Classification (IPC): 
C07D 265/36(2006.01)
A61K 31/5386(2006.01)
 A61P 25/00(2006.01)
(52) Cooperative Patent Classification (CPC):
C07D 265/36; A61P 25/00
(86) International application number:
PCT/EP2021/083544
(87) International publication number:
WO 2022/117553 (09.06.2022 Gazette 2022/23)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 01.12.2020 US 202063119690 P

(71) Applicant: AbbVie Deutschland GmbH & Co. KG
65189 Wiesbaden (DE)

(72) Inventors:
  • AMBERG, Willie
    67061 Ludwigshafen am Rhein (DE)
  • BACKFISCH, Gisela
    69412 Eberbach (DE)
  • BODIÉ, Karen
    67061 Ludwigshafen am Rhein (DE)
  • HEMPEL, Katja
    67105 Schifferstadt (DE)
  • LAPLANCHE, Loic
    67061 Ludwigshafen am Rhein (DE)
  • MEZLER, Mario
    67061 Ludwigshafen am Rhein (DE)
  • OCHSE, Michael
    67061 Ludwigshafen am Rhein (DE)
  • TURNER, Sean
    67061 Ludwigshafen am Rhein (DE)
  • VAN BERGEIJK, Jeroen
    67061 Ludwigshafen am Rhein (DE)
  • VAN DER KAM, Elizabeth
    22395 Hamburg (DE)

(74) Representative: HGF 
HGF Limited 1 City Walk
Leeds LS11 9DX
Leeds LS11 9DX (GB)

   


(54) SPIRO-CYCLIC AMINE DERIVATIVES AS S1P MODULATORS