(19)
(11) EP 4 259 191 A1

(12)

(43) Date of publication:
18.10.2023 Bulletin 2023/42

(21) Application number: 21830524.1

(22) Date of filing: 13.12.2021
(51) International Patent Classification (IPC): 
A61K 39/00(2006.01)
A61K 39/385(2006.01)
A61K 39/12(2006.01)
A61P 31/14(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 39/12; A61K 39/0011; A61K 39/385; A61K 2039/53; A61K 2039/572; A61K 2039/6075; C12N 2770/20034; A61P 31/14
(86) International application number:
PCT/IT2021/050405
(87) International publication number:
WO 2022/130432 (23.06.2022 Gazette 2022/25)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 14.12.2020 IT 202000030740

(71) Applicant: Istituto Superiore di SanitĂ 
00161 Roma (IT)

(72) Inventor:
  • FEDERICO, Maurizio Paolo Maria
    00161 Roma (IT)

(74) Representative: Gitto, Serena et al
Barzanò & Zanardo Roma S.p.A. Via Piemonte, 26
00187 Roma
00187 Roma (IT)

   


(54) NUCLEOTIDE SEQUENCE EXPRESSING AN EXTRACELLULAR VESICLE-ANCHORING PROTEIN FUSED WITH SARS-COV-2 ANTIGENS AND RELATED FUSION PROTEIN FOR USE AS VACCINE