(19)

(11)

EP 4 262 832 A1

(12)

(43) Date of publication: 25.10.2023 Bulletin 2023/43 (21) Application number: 21911996.3 (22) Date of filing: 20.12.2021

(51) International Patent Classification (IPC):  A61K 35/28(2015.01) C12N 5/00(2006.01) (52) Cooperative Patent Classification (CPC): A61K 35/28; C12N 5/0663; C12N 2523/00 (86) International application number: PCT/US2021/064433 (87) International publication number: WO 2022/140296 (30.06.2022 Gazette 2022/26)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 21.12.2020 US 202063128780 P (71) Applicant: Ossium Health, Inc. San Francisco, CA 94105 (US)	(72) Inventors: WOODS, Erik J. San Francisco, California 94105 (US) MILLER, Hannah Marie San Francisco, California 94105 (US) JOHNSTONE, Brian H. San Francisco, California 94105 (US) (74) Representative: HGF  HGF Limited 1 City Walk Leeds LS11 9DX Leeds LS11 9DX (GB)