(19)

(11)

EP 4 263 588 A1

(12)

(43) Date of publication: 25.10.2023 Bulletin 2023/43 (21) Application number: 21841114.8 (22) Date of filing: 15.12.2021

(51) International Patent Classification (IPC):  C07K 14/705(2006.01) A61P 9/00(2006.01) A61K 38/17(2006.01) A61P 11/00(2006.01) (52) Cooperative Patent Classification (CPC): C07K 14/705; C07K 2319/30; A61K 38/00; A61P 9/02 (86) International application number: PCT/US2021/063433 (87) International publication number: WO 2022/132854 (23.06.2022 Gazette 2022/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 15.12.2020 US 202063125583 P 02.11.2021 US 202163274715 P (71) Applicant: Arvada Therapeutics, Inc. Brookline, MA 02446 (US)	(72) Inventors: FOO, Shi Yin Brookline, Massachusetts 02446 (US) TYLER, Ryan Edward Arlington, Massachusetts 02476 (US) (74) Representative: Hertin und Partner Rechts- und Patentanwälte PartG mbB  Kurfürstendamm 54/55 10707 Berlin 10707 Berlin (DE)