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(11)

EP 4 267 114 A1

(12)

(43) Date of publication: 01.11.2023 Bulletin 2023/44 (21) Application number: 21840943.1 (22) Date of filing: 21.12.2021

(51) International Patent Classification (IPC):  A61K 9/51(2006.01) A61K 47/10(2017.01) A61P 3/10(2006.01) A61K 47/18(2017.01) (52) Cooperative Patent Classification (CPC): A61K 9/5146; A61K 9/5169; A61P 3/10; A61K 47/10; A61K 47/183 (86) International application number: PCT/EP2021/087031 (87) International publication number: WO 2022/136393 (30.06.2022 Gazette 2022/26)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 23.12.2020 EP 20383153 (71) Applicant: Universidad de Navarra 31009 Pamplona (Navarra) (ES)

(72) Inventors: GONZÁLEZ NAVARRO, Carlos Javier 31008 Pamplona, Navarra (ES) IRACHE GARRETA, Juan Manuel 31008 Pamplona, Navarra (ES) MARTÍNEZ-LÓPEZ, Ana Luisa 31008 Pamplona, Navarra (ES) REBOREDO FUENTES, Cristian 31008 Pamplona, Navarra (ES) VIZMANOS PÉREZ, José Luis 31008 Pamplona, Navarra (ES) (74) Representative: ABG Intellectual Property Law, S.L.  Avenida de Burgos, 16D Edificio Euromor 28036 Madrid 28036 Madrid (ES)