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EP 4 267 304 A1

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(43) Date of publication: 01.11.2023 Bulletin 2023/44 (21) Application number: 21912218.1 (22) Date of filing: 23.12.2021

(51) International Patent Classification (IPC):  B01L 3/02(2006.01) (52) Cooperative Patent Classification (CPC): B01L 3/50273; B01L 2200/16; B01L 2400/0605; B01L 2300/043; B01L 2200/0605; B01L 2400/049; B01L 7/52 (86) International application number: PCT/US2021/065045 (87) International publication number: WO 2022/140652 (30.06.2022 Gazette 2022/26)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 24.12.2020 US 202063130450 P 07.09.2021 US 202163241167 P 21.12.2021 WO PCT/US2021/065045 21.12.2021 US 202163292314 P (71) Applicant: Invivoscribe, Inc. San Diego, CA 92121 (US)

(72) Inventors: MILLER, Jeffrey Edward Del Mar, California 92024 (US) MOTTRAM, Martin Anthony Melbourn Cambridgeshire SG8 6EE (GB) KISS, Balazs Melbourn Cambridgeshire SG8 6EE (GB) MALLOY, Andrew James Melbourn Cambridgeshire SG8 6EE (GB) CRISP, Paul Malcolm Melbourn Cambridgeshire SG8 6EE (GB) CROSSLEY, Peter Lee Melbourn Cambridgeshire SG8 6EE (GB) LAING, Lauren Victoria Elizabeth Melbourn Cambridgeshire SG8 6EE (GB) MACLACHLAN, Alexander Robert Melbourn Cambridgeshire SG8 6EE (GB) (74) Representative: Hoffmann Eitle  Patent- und Rechtsanwälte PartmbB Arabellastraße 30 81925 München 81925 München (DE)