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(11)

EP 4 278 996 A3

(12)	EUROPEAN PATENT APPLICATION

(88) Date of publication A3: 24.01.2024 Bulletin 2024/04 (43) Date of publication A2: 22.11.2023 Bulletin 2023/47 (21) Application number: 23201398.7 (22) Date of filing: 02.06.2016

(51) International Patent Classification (IPC):  A61B 17/50(2006.01) A61B 17/28(2006.01) A61M 19/00(2006.01) A61B 90/00(2016.01) A61B 17/34(2006.01) A61M 5/42(2006.01) A61M 37/00(2006.01) (52) Cooperative Patent Classification (CPC): A61B 2017/3407; A61M 5/425; A61M 37/0069; A61B 17/28; A61B 17/282; A61B 17/2833; A61B 17/3494; A61B 17/50; A61B 2017/2808; A61B 2017/2837; A61B 2017/2845; A61B 2090/0811; A61B 17/3468; A61B 17/3403; A61M 19/00

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: MA MD (30) Priority: 03.06.2015 US 201562170561 P 04.06.2015 US 201562170994 P (62) Application number of the earlier application in accordance with Art. 76 EPC: 16804481.6 / 3302354 (71) Applicant: i2o Therapeutics, Inc. Cambridge, MA 02139 (US)

(72) Inventors: SMITH, Jay S. Wellesley Hills, 02481 (US) COLE, Michael R. Stratham, 03885 (US) SELLERS, James M. Eliot, 03903 (US) LAUTENBACH, Scott D. San Mateo, 94403 (US) WHITSON, Amy K. Ohio, 43221 (US) WEBER, Matthew Berkley, 02779 (US) (74) Representative: Mewburn Ellis LLP  Aurora Building Counterslip Bristol BS1 6BX Bristol BS1 6BX (GB)