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EP 4 284 930 A2

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(88) Date of publication A3: 09.09.2022 (43) Date of publication: 06.12.2023 Bulletin 2023/49 (21) Application number: 22702677.0 (22) Date of filing: 26.01.2022

(51) International Patent Classification (IPC):  C12N 15/11(2006.01) A61K 31/7088(2006.01) C12N 15/113(2010.01) (52) Cooperative Patent Classification (CPC): C12N 15/111; C12N 15/113; C12N 2310/11; C12N 2320/33; C12N 2310/321; C12N 2310/315 (86) International application number: PCT/EP2022/051790 (87) International publication number: WO 2022/162020 (04.08.2022 Gazette 2022/31)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 26.01.2021 EP 21153508 (71) Applicant: Syddansk Universitet 5230 Odense M (DK)	(72) Inventors: ANDRESEN, Brage, Storstein 8230 Åbyhøj (DK) DOKTOR, Thomas, Koed 5672 Broby (DK) HOLM, Lise, Lolle 4700 Næstved (DK) PETERSEN, Ulrika Simone Spangsberg 5000 Odense C (DK) BRUUN, Gitte, Hoffmann 5260 Odense S (DK) (74) Representative: Plougmann Vingtoft a/s  Strandvejen 70 2900 Hellerup 2900 Hellerup (DK)