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EP 4 285 106 A1

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(43) Date of publication: 06.12.2023 Bulletin 2023/49 (21) Application number: 22702301.7 (22) Date of filing: 26.01.2022

(51) International Patent Classification (IPC):  G01N 21/65(2006.01) G01N 33/18(2006.01) G01N 33/10(2006.01) G01N 33/543(2006.01) (52) Cooperative Patent Classification (CPC): G01N 33/1813; G01N 33/10; G01N 21/658; G01N 33/587 (86) International application number: PCT/GB2022/050207 (87) International publication number: WO 2022/162362 (04.08.2022 Gazette 2022/31)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 26.01.2021 GB 202101061 (71) Applicant: The Queen's University of Belfast Belfast BT7 5NN (GB)

(72) Inventors: ELLIS, Matthew Belfast Belfast District BT7 1HF (GB) LOGAN, Natasha Belfast Belfast District BT7 1HF (GB) HAUGHEY, Simon Belfast Belfast District BT7 1HF (GB) ELLIOT, Chris Belfast Belfast District BT7 1HF (GB) TATE, James Belfast Belfast District BT7 1HF (GB) CAO, Cuong Belfast Belfast District BT7 1HF (GB) FRANCO, Javier Lou Belfast Belfast District BT7 1HF (GB) (74) Representative: Murgitroyd & Company  Murgitroyd House 165-169 Scotland Street Glasgow G5 8PL Glasgow G5 8PL (GB)