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EP 4 288 062 A1

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(43) Date of publication: 13.12.2023 Bulletin 2023/50 (21) Application number: 21925083.4 (22) Date of filing: 27.12.2021

(51) International Patent Classification (IPC):  A61K 31/661(2006.01) A61K 9/00(2006.01) (52) Cooperative Patent Classification (CPC): A61K 31/661; A61K 9/209; A61K 9/2081; A61K 9/2013 (86) International application number: PCT/US2021/065225 (87) International publication number: WO 2022/169520 (11.08.2022 Gazette 2022/32)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 05.02.2021 US 202117168365 30.03.2021 US 202117217656 28.07.2021 US 202117387059 03.09.2021 US 202117466016 03.09.2021 US 202117465966 (71) Applicant: Epalex Corporation Mountain View, CA 94304 (US)

(72) Inventors: KRILL, Steven, L. San Clemente, CA 92673 (US) CHEN, Feng-Jing Irvine, CA 92603 (US) MURPHY, Randall, B. Mountain View, CA 94304 (US) ROGAWSKI, Michael, A. Far Hills, NJ 07931 (US) HELLER, Allen Woodbridge, CT 06525 (US) MAGRAB, Edward, Brendan Far Hills, NJ 07931 (US) ANDREW, Samuel Mountain View, California 94040 (US) (74) Representative: Høiberg P/S  Adelgade 12 1304 Copenhagen K 1304 Copenhagen K (DK)