(19)
(11) EP 4 288 529 A2

(12)

(88) Date of publication A3:
29.09.2022

(43) Date of publication:
13.12.2023 Bulletin 2023/50

(21) Application number: 22710773.7

(22) Date of filing: 02.02.2022
(51) International Patent Classification (IPC): 
C12N 9/10(2006.01)
C12N 15/62(2006.01)
C07K 14/705(2006.01)
C12N 15/52(2006.01)
A61P 35/00(2006.01)
C07K 14/725(2006.01)
(52) Cooperative Patent Classification (CPC):
C12N 9/104; C12Y 203/02; C07K 2319/00; C12N 15/62; C07K 2319/81; A61P 35/00; C07K 14/705; C07K 14/7051; C07K 14/70521; C07K 2319/01
(86) International application number:
PCT/US2022/014998
(87) International publication number:
WO 2022/169913 (11.08.2022 Gazette 2022/32)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA ME
Designated Validation States:
KH MA MD TN

(30) Priority: 02.02.2021 US 202163144895 P
26.09.2021 US 202163248516 P

(71) Applicant: Outpace Bio, Inc.
Seattle, WA 98109 (US)

(72) Inventors:
  • MOFFETT, Howell
    Seattle, Washington 98102 (US)
  • NGUYEN, Duy
    San Francisco, California 94080 (US)
  • LANGAN, Robert
    Seattle, Washington 98122 (US)
  • BOYKEN, Scott
    Seattle, Washington 98125 (US)
  • LAJOIE, Marc
    Seattle, Washington 98125 (US)
  • FOIGHT, Glenna
    Houston, Texas 77004 (US)

(74) Representative: Cooley (UK) LLP 
22 Bishopsgate
London EC2N 4BQ
London EC2N 4BQ (GB)

   


(54) SYNTHETIC DEGRADER SYSTEM FOR TARGETED PROTEIN DEGRADATION