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(11)

EP 4 291 027 A1

(12)

(43) Date of publication: 20.12.2023 Bulletin 2023/51 (21) Application number: 21925945.4 (22) Date of filing: 15.12.2021

(51) International Patent Classification (IPC):  A01N 1/02(2006.01) A61K 38/51(2006.01) A61P 15/08(2006.01) A61K 35/54(2015.01) C07K 14/415(2006.01) A01K 67/02(2006.01) C12N 9/88(2006.01) A61K 35/52(2015.01) C12N 5/076(2010.01) (52) Cooperative Patent Classification (CPC): A61K 35/52; A61K 35/54; A61K 38/51; A61P 15/08; C12N 9/88; C12Y 402/01092; C12N 5/061; C12N 5/0604; C12N 2501/71; A01K 2207/10 (86) International application number: PCT/NZ2021/050222 (87) International publication number: WO 2022/173313 (18.08.2022 Gazette 2022/33)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 11.02.2021 US 202163148476 P (71) Applicant: Synthase Biotech Limited Parnell Auckland, 1052 (NZ)	(72) Inventors: HODGKINSON, Steven Charles Hamilton, 3281 (NZ) BACKHAUS, Max Daniel Hamilton, 3214 (NZ) (74) Representative: J A Kemp LLP  80 Turnmill Street London EC1M 5QU London EC1M 5QU (GB)