(19)

(11)

EP 4 294 529 A1

(12)

(43) Date of publication: 27.12.2023 Bulletin 2023/52 (21) Application number: 22706805.3 (22) Date of filing: 17.02.2022

(51) International Patent Classification (IPC):  A61P 35/00(2006.01) C07K 16/28(2006.01) C07K 16/30(2006.01) C07K 16/40(2006.01) A61K 35/17(2015.01) C12N 5/0783(2010.01) C07K 16/32(2006.01) (52) Cooperative Patent Classification (CPC): C07K 16/2809; C07K 2317/34; C07K 2317/92; C07K 2317/73; C07K 2317/74; C07K 2317/732; C07K 2317/734; C07K 16/2863; C07K 16/2803; C07K 16/32; C07K 16/40; C07K 16/30; C07K 16/2818; C07K 16/2878; C07K 2317/31; Y02A 50/30 (86) International application number: PCT/EP2022/054011 (87) International publication number: WO 2022/175414 (25.08.2022 Gazette 2022/34)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA ME Designated Validation States: KH MA MD TN (30) Priority: 17.02.2021 GB 202102224 14.08.2021 GB 202111685 (71) Applicants: GammaDelta Therapeutics Limited London W2 6BD (GB) F-star Therapeutics Limited Cambridge, CB22 3AT (GB)

(72) Inventors: TUNA, Mihriban London W12 7FQ (GB) UDEN, Mark London W12 7FQ (GB) FREEDMAN, Joshua London W12 7FQ (GB) MOUNT, Natalie London W12 7FQ (GB) (74) Representative: Heath, Abigail  Kilburn & Strode LLP Lacon London 84 Theobalds Road London WC1X 8NL London WC1X 8NL (GB)