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<SDOBI lang="en"><B000><eptags><B001EP>ATBECHDEDKESFRGBGRITLILUNLSEMCPTIESILTLVFIROMKCYALTRBGCZEEHUPLSK..HRIS..MTNORS..SM..................</B001EP><B005EP>J</B005EP><B007EP>0009290-CORR01</B007EP></eptags></B000><B100><B110>4296373</B110><B120><B121>CORRECTED EUROPEAN PATENT SPECIFICATION</B121></B120><B130>B8</B130><B132EP>B1</B132EP><B140><date>20250326</date></B140><B150><B151>W1</B151><B153>73</B153><B155><B1551>de</B1551><B1552>Bibliographie</B1552><B1551>en</B1551><B1552>Bibliography</B1552><B1551>fr</B1551><B1552>Bibliographie</B1552></B155></B150><B190>EP</B190></B100><B200><B210>23189043.5</B210><B220><date>20191004</date></B220><B240><B241><date>20240724</date></B241></B240><B250>en</B250><B251EP>en</B251EP><B260>en</B260></B200><B300><B310>201862741466 P</B310><B320><date>20181004</date></B320><B330><ctry>US</ctry></B330><B310>201962832560 P</B310><B320><date>20190411</date></B320><B330><ctry>US</ctry></B330></B300><B400><B405><date>20250326</date><bnum>202513</bnum></B405><B430><date>20231227</date><bnum>202352</bnum></B430><B450><date>20250219</date><bnum>202508</bnum></B450><B452EP><date>20240923</date></B452EP><B480><date>20250326</date><bnum>202513</bnum></B480></B400><B500><B510EP><classification-ipcr sequence="1"><text>C12Q   1/6806      20180101AFI20231215BHEP        </text></classification-ipcr><classification-ipcr sequence="2"><text>C12Q   1/6865      20180101ALI20231215BHEP        </text></classification-ipcr></B510EP><B520EP><classifications-cset><classification-cset group-number="2"><classification-cpc rank="1"><text>C12Q   1/6806      20130101 LI20200117BHEP        </text></classification-cpc><classification-cpc rank="2"><text>C12Q2525/131       20130101 LI20200117BHEP        </text></classification-cpc><classification-cpc rank="3"><text>C12Q2525/143       20130101 LI20200117BHEP        </text></classification-cpc><classification-cpc rank="4"><text>C12Q2525/204       20130101 LI20200117BHEP        </text></classification-cpc><classification-cpc rank="5"><text>C12Q2535/122       20130101 LI20200117BHEP        </text></classification-cpc><classification-cpc rank="6"><text>C12Q2545/101       20130101 LI20200117BHEP        </text></classification-cpc><classification-cpc rank="7"><text>C12Q2545/113       20130101 LI20200117BHEP        </text></classification-cpc></classification-cset><classification-cset group-number="3"><classification-cpc rank="1"><text>C12Q   1/6865      20130101 LI20231113BHEP        </text></classification-cpc><classification-cpc rank="2"><text>C12Q2525/131       20130101 LI20231113BHEP        </text></classification-cpc><classification-cpc rank="3"><text>C12Q2525/143       20130101 LI20231113BHEP        </text></classification-cpc><classification-cpc rank="4"><text>C12Q2535/122       20130101 LI20231113BHEP        </text></classification-cpc><classification-cpc rank="5"><text>C12Q2545/101       20130101 LI20231113BHEP        </text></classification-cpc></classification-cset></classifications-cset><classifications-cpc><classification-cpc sequence="1"><text>C12Q   1/6806      20130101 FI20200117BHEP        </text></classification-cpc><classification-cpc sequence="2"><text>C12Q2600/166       20130101 LA20221123BHEP        </text></classification-cpc><classification-cpc sequence="3"><text>C12Q   1/6876      20130101 LI20221123BHEP        </text></classification-cpc><classification-cpc sequence="4"><text>C12Q2525/131       20130101 LA20231113BHEP        </text></classification-cpc><classification-cpc sequence="5"><text>C12Q2525/143       20130101 LA20231113BHEP        </text></classification-cpc><classification-cpc sequence="6"><text>C12Q2535/122       20130101 LA20231113BHEP        </text></classification-cpc><classification-cpc sequence="7"><text>C12Q2545/101       20130101 LA20231113BHEP        </text></classification-cpc><classification-cpc sequence="8"><text>C12Q   1/6865      20130101 LI20231113BHEP        </text></classification-cpc></classifications-cpc></B520EP><B540><B541>de</B541><B542>NORMALISIERUNGSSTEUERUNG ZUR VERWALTUNG GERINGER PROBENEINGABEN IN DER NEXT-GENERATION-SEQUENZIERUNG</B542><B541>en</B541><B542>NORMALIZATION CONTROLS FOR MANAGING LOW SAMPLE INPUTS IN NEXT GENERATION SEQUENCING</B542><B541>fr</B541><B542>COMMANDES DE NORMALISATION POUR GÉRER DE FAIBLES ENTRÉES D'ÉCHANTILLON DANS LE SÉQUENÇAGE DE NOUVELLE GÉNÉRATION</B542></B540><B560><B562><text>LESHKOWITZ DENA ET AL: "Using Synthetic Mouse Spike-In Transcripts to Evaluate RNA-Seq Analysis Tools", PLOS ONE, vol. 11, no. 4, 21 April 2016 (2016-04-21), pages e0153782, XP093100733, Retrieved from the Internet &lt;URL:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839710/pdf/pone.0153782.pdf&gt; DOI: 10.1371/journal.pone.0153782</text></B562><B562><text>SIMON A HARDWICK ET AL: "Spliced synthetic genes as internal controls in RNA sequencing experiments", NATURE METHODS, vol. 13, no. 9, 1 September 2016 (2016-09-01), New York, pages 792 - 798, XP055535717, ISSN: 1548-7091, DOI: 10.1038/nmeth.3958</text></B562><B562><text>MAURO D. LOCATI ET AL: "Improving small RNA-seq by using a synthetic spike-in set for size-range quality control together with a set for data normalization", NUCLEIC ACIDS RESEARCH ADVANCE ACCESS, vol. 43, no. 14, 18 August 2015 (2015-08-18), GB, pages e89 - e89, XP055386708, ISSN: 0305-1048, DOI: 10.1093/nar/gkv303</text></B562></B560></B500><B600><B620><parent><pdoc><dnum><anum>19794317.8</anum><pnum>3861135</pnum></dnum><date>20191004</date></pdoc></parent></B620></B600><B700><B720><B721><snm>HARNESS, Eric</snm><adr><city>CA 94086 Sunnyvale</city><ctry>US</ctry></adr></B721><B721><snm>NAGESH, Vaishnavi</snm><adr><city>MA 02141, Cambridge</city><ctry>US</ctry></adr></B721><B721><snm>BENTLEY, Lloyd Gordon</snm><adr><city>MA 02141 Cambridge</city><ctry>US</ctry></adr></B721><B721><snm>CARPENTER, Meredith L.</snm><adr><city>CA 94401 San Mateo</city><ctry>US</ctry></adr></B721></B720><B730><B731><snm>Arc Bio, LLC</snm><iid>102078219</iid><irf>JCL/P222132EP01</irf><adr><str>100 Enterprise Way</str><city>Scotts Valley, CA 95066</city><ctry>US</ctry></adr></B731></B730><B740><B741><snm>Boult Wade Tennant LLP</snm><iid>101370347</iid><adr><str>Salisbury Square House
8 Salisbury Square</str><city>London EC4Y 8AP</city><ctry>GB</ctry></adr></B741></B740></B700><B800><B840><ctry>AL</ctry><ctry>AT</ctry><ctry>BE</ctry><ctry>BG</ctry><ctry>CH</ctry><ctry>CY</ctry><ctry>CZ</ctry><ctry>DE</ctry><ctry>DK</ctry><ctry>EE</ctry><ctry>ES</ctry><ctry>FI</ctry><ctry>FR</ctry><ctry>GB</ctry><ctry>GR</ctry><ctry>HR</ctry><ctry>HU</ctry><ctry>IE</ctry><ctry>IS</ctry><ctry>IT</ctry><ctry>LI</ctry><ctry>LT</ctry><ctry>LU</ctry><ctry>LV</ctry><ctry>MC</ctry><ctry>MK</ctry><ctry>MT</ctry><ctry>NL</ctry><ctry>NO</ctry><ctry>PL</ctry><ctry>PT</ctry><ctry>RO</ctry><ctry>RS</ctry><ctry>SE</ctry><ctry>SI</ctry><ctry>SK</ctry><ctry>SM</ctry><ctry>TR</ctry></B840><B880><date>20240124</date><bnum>202404</bnum></B880></B800></SDOBI>
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